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  Indian J Med Microbiol
 

Figure 3: Histopathology of the paraganglioma. (a) Gross view of the specimen shows a yellowish to brownish elastic and encapsulated mass. (b and c) Histopathological views show the paraganglioma composed of sheet, zellballen growth of epithelioid, polygonal, tumor cells with amphophilic, finely granular, cytoplasm, and centralized nuclei with conspicuous nucleoli(b: [H and E, ×40] and c: [H and E, ×100]). The immunostains (images not shown) show synaptophysin (+), chromogranin (+), and Melan A (−) in tumor cells. The S100 highlights sustentacular cells. The PHH3 shows a mitotic rate <1 mitosis/10 HPF in tumor cells

Figure 3: Histopathology of the paraganglioma. (a) Gross view of the specimen shows a yellowish to brownish elastic and encapsulated mass. (b and c) Histopathological views show the paraganglioma composed of sheet, zellballen growth of epithelioid, polygonal, tumor cells with amphophilic, finely granular, cytoplasm, and centralized nuclei with conspicuous nucleoli(b: [H and E, ×40] and c: [H and E, ×100]). The immunostains (images not shown) show synaptophysin (+), chromogranin (+), and Melan A (−) in tumor cells. The S100 highlights sustentacular cells. The PHH3 shows a mitotic rate <1 mitosis/10 HPF in tumor cells