• Users Online: 105
  • Print this page
  • Email this page
 
ORIGINAL ARTICLE
Ahead of Print

Sonographic assessment of some abdominal organs in children with sickle cell disease in Ilorin, Nigeria


1 Department of Radiology, University of Ilorin Teaching Hospital, Ilorin, Kwara State, Nigeria
2 Department of Radiology and Radiological Sciences, Nnamdi Azikwe University, Nnewi Campus, Nnewi, Nigeria
3 Department of Radiography, Bayero University Kano, Kano, Nigeria
4 Department of Radiotherapy, Usmanu Dan Fodio University Teaching Hospital, Sokoto, Nigeria

Correspondence Address:
Basirat Muftaudeen,
C/O Alhaji Toyin, No. 25 Jabata Compound, Princess Road, Ilorin, Kwara State
Nigeria
Login to access the Email id

Source of Support: None, Conflict of Interest: None

Background: The irregular sickle cells can block blood vessels, causing tissue and organ damage and in most cases presented with pain as a result of organ ischemia. Ultrasonography is an easily available instrument for investigating abdominal organs which are most commonly affected by sickle cell disease (SCD). This study was aimed to assessing liver, gall bladder, spleen, and kidney in children with SCD in Ilorin, Kwara State. Materials and Methods: A prospective cross-sectional study was conducted among children with SCD in Ilorin from September 2017 to April 2018. An ethical approval was obtained from the Human Research and Ethics Committee of the Kwara State Ministry of Health. In this study, 106 children with SCD and 106 normal children for control were included. Abdominal ultrasound scan was performed on all the selected subjects and the findings were recorded on the data capture sheet. Descriptive and inferential statistic was used in the data analysis, SPSS version 20 was used and the P = 0.05. Results: In the children with SCD, hepatomegaly was found in 45 (42.5%), 29 (27.4%) had coarse echo pattern of liver and 16 (15.1%) had hyperechoic liver, 5 (4.7%) had gallbladder stone, 2 (1.9%) had gallbladder sludge, and 6 (5.6%) had thickened gallbladder wall. Twenty-five (23.6%) had splenomegaly, and 7 (6.6%) had autosplenectomy. Four (3.8%) showed reduced corticomedullary differentiation in each kidney, five (4.7%) in each kidney had mild calyceal dilatation. One (0.9%) had mild calyceal dilatation with reduced corticomedullary differentiation with accompanying loss of renal sinus fat. Conclusion: Abdominal ultrasound imaging for patients with SCD showed a high incidence of abdominal abnormalities, especially in solid organs such as liver, kidney, and spleen.


Print this article
Search
 Back
 
  Search Pubmed for
 
    -  Muftaudeen B
    -  Eze JC
    -  Sidi M
    -  Miftaudeen MN
 Citation Manager
 Article Access Statistics
 Reader Comments
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed526    
    PDF Downloaded23    

Recommend this journal