| ORIGINAL ARTICLE |
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| Year : 2022 | Volume
: 30
| Issue : 4 | Page : 272-276 |
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Prognostic value of porta-hepatis lymphadenopathy in children with hepatitis A
Amin Mashhadi1, Manijeh Khalili2, Alireza Ansari Moghaddam3, Mohadeseh Zadehmir1
1 Department of Radiology, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran
2 Children and Adolescent Health Research Center, Resistant Tuberculosis Institute, Zahedan University Medical Sciences, Zahedan, Iran
3 Health Promotion Research Center, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran
Correspondence Address:
Dr. Mohadeseh Zadehmir
Department of Radiology, School of Medicine, Zahedan University of Medical Sciences, Zahedan
Iran
 Source of Support: None, Conflict of Interest: None
DOI: 10.4103/jmu.jmu_196_21
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Background: The present study aimed to investigate the prognostic value of porta-hepatis lymphadenopathy (PHL) in children with hepatitis A virus. Methods: The present prospective cohort study included 123 pediatric patients with a definite diagnosis of hepatitis A who were divided into two groups based on the presence or absence of PHL in their abdominal ultrasound: Group A included the patients with a porta-hepatis lymph node of >6 mm in diameter, whereas the patients with a porta-hepatis lymph node of <6 mm in diameter were classified in Group B. The patients were also classified based on the presence or absence of para-aortic lymphadenopathy: Group C had bisecting para-aortic lymph nodes, whereas Group D did not have such findings in their ultrasound. Afterward, the groups were compared in laboratory investigation results and hospital stay. Results: According to our results, Group A (n = 57) was significantly higher in aspartate and alanine aminotransferase and alkaline phosphatase levels compared to Group B (P < 0.05), whereas these two groups were not significantly different in the hospital stay. Furthermore, except bilirubin, all laboratory test results were significantly higher in Group C (n = 3) than in Group D. However, there was no significant correlation between the patients' prognosis with the absence or presence of porta-hepatis or para-aortic lymphadenopathy. Conclusion: We concluded that there was no significant relationship between porta-hepatis or para-aortic lymphadenopathy and the prognosis of the children with hepatitis A. However, ultrasound findings can help determine the disease severity in pediatric patients with hepatitis A.
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